Peter McFetridge

Co-Founder, Chief Scientific Officer

Pete McFetridge has a PhD in Chemical Engineering from Bath University in the United Kingdom and is Associate Professor of Biomedical Engineering at UF. He has pioneered novel growth factor technologies and bioreactor designs for tissue engineering and regenerative medicine. From the beginning of his independent career as an Assistant Research Professor, Dr. Mcfetridge has focused on exploring a variety of materials that have both direct clinical application as well as the potential to deepen the understanding of both biological and engineering principles.

From a materials perspective, most of Dr. McFetridge’s work utilizes human tissue that is processed into functional biomaterials – termed ex vivo-derived tissue implants. There are several important components to this process, not least the removal of the existing cellular debris and other soluble factors to ensure immune compliance. His research focuses on both the general processing conditions (solvents, surfactants etc.) as well as understanding key events and influences that drive active and functional regeneration. Dr. McFridge’s overarching research objective is to create functional organs that can be used in organ replacement therapies

Dr. McFetridge’s research has been at the forefront of biomaterials applications using human placental tissues as both direct implants and as platforms for guided tissue regeneration. These materials have rapidly found a place in the clinic in variety of applications, blood vessels, tendons, nerves. Dr. McFetridge has been recognized for his innovative successes as a two-time recipient of the University of Florida Technology Innovator Award and the Innovator of the Year by The Journal Record. His research and excellence in science has been recognized through the Japanese BME TOIN award and by the Japan Research Institute of Material Technology.

Selected Publications

  • Daniel J., Abe K., McFetridge PS. Development of the human umbilical vein scaffold for cardiovascular tissue engineering applications. ASAIO J. 2005; 51: 252-261

  • Salma Amensag, Peter S. McFetridge. Tuning Scaffold Mechanics by Laminating Native Extracellular Matrix Membranes and Effects on Early Cellular Remodeling. Journal of Biomedical Materials Research Part 2014 Ma; 102(5):1325-3

  • Joseph Uzarski, Aurore Van de Walle, Peter S. McFetridge. Pre-implantation Processing of Ex Vivo-Derived Vascular Biomaterials: Effects on Peripheral Cell Adhesion. Journal of Biomedical Materials Research: Part A 101A Issue: 1 Pages: 123-131 DOI: 10.1002/jbm.a.34308. Jan 2013

  • Marc Moore, Vittoria Pendolfe, Peter S. McFetridge Novel human-derived extracellular matrix induces in vitro and in vivo vascularization and inhibits fibrosis. Biomaterials, Volume: 49 Pages: 37-46 Published: MAY 2015

  • Marc C. Moore, Aurore Van De Walle, Jerry Chang, Cassandra Juran and Peter S. McFetridge

  • Human Perinatal-Derived Biomaterials, Advanced Healthcare Materials, 7 AUG 2017, DOI: 10.1002/adhm.201700345

  • Joseph S. Uzarski, Aurore B. Van de Walle, and Peter S. McFetridge. In vitro method for real-time, direct observation of cell-vascular graft interactions under simulated blood flow. Tissue engineering C. Volume: 20 Issue: 2 pg. 116-128 2014.

  • Kamil Nowiki, Edward Scott, Yong He, Peter S. McFetridge, Brian Hoh. A novel high-throughput in vitro model for identifying hemodynamic-induced inflammatory mediators of cerebral aneurysm formation. Hypertension, Dec;64(6):1306-13 2014

  • Aurore B. Van de Walle, Joseph S. Uzarski and Peter S. McFetridge. The consequence of biologic graft processing on blood interface biocompatibility and mechanics. Cardiovascular Engineering and Technology, Volume: 6 Issue: 3 Pages: 303-313 Published: SEP 2015

  • Nimmagadda A., Thurston K., Nollert M., Peter S. McFetridge, Chemical Modification of SWNT Alters in vitro Cell-SWNT Interactions. Journal of Biomedical Materials Research. 2006; 76A, 3: 614-625

  • Crouzier T., Nimmagadda A., Nollert U., and McFetridge P.S. Modification of SWNT surface chemistry improves aqueous solubility and enhances cellular interactions. Langmuir 2008 Vol 24, Issue 22, pg. 13173-13181.

  • Zehra Tosun, Peter S. McFetridge. A composite SWNT–collagen matrix: characterization and preliminary assessment as a conductive peripheral nerve regeneration matrix. Journal of Neural Engineering. 2010 J. Neural Eng. December 7 (7) 066002